Parkinson’s disease is a neurological disease, usually occurs when a group of cells in the brain degenerate, unable to control muscle movement, making it difficult for people to walk, slow and slow leg movements. stiff hands. As the disease progresses, it can affect nerve cells, causing a lack of dopamine. Let’s find out Parkinson disease symptoms in this article!
Currently, there is still no method to completely cure patients with Parkinson’s disease, but only measures to improve quality of life, and delay the progression of the disease.
So what is Parkinson’s disease? What causes Parkinson’s disease? And in Parkinson’s disease hereditary?
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Parkinson’s disease causes
Scientists do not have an explanation for why brain cells that produce neurotransmitters degenerate and die, but can only suggest a number of different disease-causing factors such as age (older age), due to genetics, environmental factors, and maybe even viruses.
Parkinson’s disease symptoms
Patients with Parkinson’s disease have some of the following signs and symptoms:
Personality Changes: Since the brain is normally responsible for thinking, acting, seeing, and reacting to situations, any change in personality is an early cause of Parkinson’s disease.
Slow coordination of activities: this is one of the most obvious signs of Parkinson’s disease in its early stages. Expressions such as any change of posture such as turning the head, turning, buttoning, or tying shoelaces are done at a slow, unclear speed.
Decreased sense of smell: in the early stages, Parkinson’s disease often affects a person’s sense of smell, making the patient unable to distinguish the smell of food, this condition is getting worse if not treated promptly. time.
Intestinal problems: signs such as constipation or digestive problems are common, especially in older people.
Shoulder pain: persistent shoulder pain, even with medical intervention such as medication without relief, is one of the signs of Parkinson’s disease.
Fatigue: Frequent fatigue associated with one of the early signs of Parkinson’s disease is a high risk of.
There are some changes in the habits of daily living such as changes in handwriting, voice, and mood swings.
Some symptoms of the disease are easy to encounter such as slight tremors when the disease is advanced, problems with movement, sleep disturbances, facial paralysis, fainting, and loss of balance.
The risk of Parkinson’s disease is usually high in the elderly, increasing gradually with age, especially 60 years of age and older. In terms of gender, men are more likely to develop Parkinson’s disease than women.
Factors that increase the risk of Parkinson’s disease such as age, genetic factors, sex, and exposure to toxins.
The four main motor symptoms of Parkinson’s disease are tremor, rigidity, bradykinesia, and postural instability, as defined by the acronym TRAP (tremor, rigidity, akinesia (or bradykinesia), and postural instability). Secondary motor symptoms include decreased swinging of the arms, decreased blinking frequency, masked facial expressions (hypomimia), decreased voice volume (hypophonia), and difficulty turning in bed.
Trembling refers to pulsating pulsation around a fixed point during rest or non-postural position. Tremor is often the first motor symptom of Parkinson’s disease and occurs in about 90% of patients at some point in their lives.
While the tremor of Parkinson’s disease is typically a resting tremor, 50% of patients may also present with a tremor that may reappear with the extension of the arms. The tremor begins asymmetrically and is characterized by pronation and back, or ball roll, that eventually affects the opposite side of the body. Tremors may be poorly responsive to pharmacological treatments, including levodopa.
Stiffness refers to stiffness or resistance of a limb when it is passively flexed, activating both agonist and antagonist muscles, and may also be called a cog wheel. Stagnation means slow movement (no movement means no movement) and can occur both during the initiation and maintenance of movement.
Postural instability, or balance dysfunction, occurs later in the course of the disease, about a decade after the initial diagnosis. Postural instability is correlated with disease severity and is demonstrated by tensile testing. It is a symptom of levodopa resistance, as opposed to bradykinesia, muscle stiffness, and tremor. Postural instability is a major cause of falls, causing hip fractures, loss of independence, and home nursing for patients.
Other terms associated with Parkinson’s disease symptoms include dyskinesia, also called levodopa dyskinesia, which refers to abnormal, involuntary, chorea-like movements that can be in the limbs, head, and trunk. Levodopa-induced dyskinesia may also present with swagger, myoclonus, dystonia, or a combination of these movements.
Levodopa-induced dyskinesia can be further classified as peak-dose dyskinesia, time-off or wearing-off dyskinesia, or biphasic dyskinesia. Biphasic dyskinesia begins shortly after taking levodopa, followed by improvement in Parkinson’s symptoms and dyskinesia, and then a return of dyskinesia as dopamine levels decrease.
Dystonia refers to prolonged, involuntary muscle contractions with abnormal postures, often in the extremities. Dystonicity often occurs with times of low dopamine levels, often during the early morning hours. Patients may twist toes or invert the foot due to instep or plantar flexion, which can lead to leg cramps or pain. Dystonicity can also occur at peak dose, biphasic, or the “off” state.
Motor oscillation refers to an “off” time, when there is a poor response to levodopa, alternating with an “on” period, which is a time of improvement in function. Motor oscillations occur as the disease progresses, possibly because of fluctuating stimulation from levodopa on postsynaptic receptors. Off periods are predictable, during which symptoms emerge before the next dose, or may not be predictable. Dose failure means that levodopa has a slow clinical effect.
Freeze is described by Giladi and Nieuwboer as “an episodic inability (lasting a few seconds) followed by effective walking with no known cause other than Parkinson’s syndrome or gait disorders. severity level. This is most common while turning and starting to walk, but can also be seen when confined to confined spaces, when stressed, and when distracted.” Patients feel that their feet are glued to the ground, and this sensation is often essentially intermittent.
How to prevent Parkinson
The preventive measures for Parkinson’s disease are as follows:
Sunbathe regularly to supplement enough vitamin D for the body. According to research by scientists, most patients with Parkinson’s disease have low levels of Vitamin D.
Drinking green tea daily prevents toxins that can kill nerve cells from entering the brain.
Proper use of coffee helps prevent many health problems, including limiting the risk of disease.
Stay away from toxic environments, especially pesticides.
Supplement nutrients from flavonoid-rich fruits.
There is a scientific exercise regime.
Final thought
To diagnose Parkinson’s disease, doctors do not have any tests that can be used to diagnose and confirm Parkinson’s disease but only conclude through the patient’s signs over a long time to conclude.
Top News hopes this article can help you learn more about Parkinson’s disease symptoms and wishes you all the best!
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